Naming:
-olol: beta blockers

Receptors:
beta 1
beta 2
non-selective
(similar to Propranolol for being non-selective beta blockers)

Use:
Angina --------  blocking effects of beta 1 beta 2
HTN ---- blocking effects of beta 1 beta 2
Glaucoma ---------- (decreased intraocular pressure) 


Mnemonics:
 Timolol => Timid -olol: timid = not-selective, just timid in any and every situation => non-selective beta => manifestation: afraid being the light of the party (glaucoma), easily get a chest pain (angina) in any situation, easily angered (le^n ma'u)

Tommy the Timid Turtle => big eye (glaucoma), always afraid  and anxious = adrenergic innervation = chest pain (angina) & HTN

History:

Dr. Holland's influence in glaucoma research enabled a Tulane resident to publish a singal paper. Dr. William A. Hubbard was able to perform a research project in conjunction with the Merck Sharp & Dohme company, testing a novel glaucoma agent. The drug was timolol, and Dr. Hubbard published the very first article in the world literature on human IOP reduction by timolol. This article appeared in Investigative Ophthalmology, 15(6): 489-92, 1976. Timolol became the most important advancement in medical glaucoma treatment in decades. (1)

Imagine using a computer from the mid 1970s — or that “state of the art” item of stereo equipment, the 8-track tape player — to listen to your music. Funny, right? Both are enormous, by today's standards, operate slowly and don't perform as well as their modern counterparts. They're dinosaurs.
Yet glaucoma care providers are still relying heavily on a drug that was born when 8-track tape players were the epitome of cool: timolol. In medicine, a field in which revolutions occur regularly, timolol has yet to find itself on the ash-heap of history. (2) 

(1): https://tulane.edu/som/departments/ophthalmology/history-first-timolol-paper.cfm
(2): http://www.ophthalmologymanagement.com/articleviewer.aspx?articleID=106705