Niacin
Slo-Niacin
Niacor Niacinol
NIAC
Slo-Niacin Niacor Niacinol
Mnemonics: Ni-hAo-wo-shin (NI-A-CIN)=>Chinese
greetings when you eat greasy (high cholesterol) foods
Mech.: chinese greasy foods => need to
decrease all of the bad guys=>
decrease VLDL & triglycerids & LDL-C
Niacin => red
face => flushing (Chinese love red)
Cholesterol
Absorption Inhibitor
Ezetimibe
Mech.: inhibit absorption of cholesterol by the small
intestine
Mnemonics for mech.:
-
I just think of it acting according to the EZest mechanism out
there. The drug doesn't bother entering the blood, hepatocytes, or endothelial
cells; it just stays in the GI and does its work there.
History background: At first, when this drug first
come out, it was thought to be sooo cool. This is bc while vastatin only lower
cholesterol by 6%. This drug is able to lower by like 80% of triglycerides alone.
Using with vastatin, if you need to increase dosage for the right effect, it
would be double triple the dose running the higher side effects => stocks
went sky high for the drugs. However, after the RCT’s showed that the drugs
does not really have any great outcomes despite its mechanism, stocks
plummetted
Mnemonics for name: E-z-e-timid-tribe
=> the easy timid tribe takes up only a small areas = small intestines. It’s so timid = not much needed to get the
criminals away. It’s a tribe trying to get the criminals (cholesterol)
away from its small intestines land bc they don’t want any criminals on their
land.
Therefore => Use:
- in combo w/
vastatin when pts unable to achieve
target LDL: ezetimabide/simvastatin
- Or, in pt intolerant w/
vastatin
Drug name: Rosuvastatin
Drug class: HMG-CoA Reductase
Drug use: High intensity therapy
Drug dose: 20-40
Mnemonics for Rosuvastatin drug name: pRO-SUmo-VAST-STATUE
Mnemonics for Rosuvastatin: pRO-SUmo-VAST-STATUEcame in like a hurricane blew these HMG guys off like crazy!
Mnemonics for Rosuvastatin use: pRO-SUmo-VAST-STATUE=> high profile!
Mnemonics for drug dose: best time gungho time 20 and go double that 20*2 = 40 => best age to do sumo!
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| pRO-SUmo-VAST-STATue (Rosuvastatin) |
~WonderMe
Drug name: atorvastatin
Drug class: HMG-CoA Reductase => disable the enzymes that make cholesterol
Dosage:
40-80mg
Indication: For high intensity statin therapy
Timing: All -vastatin is to be taken at night when the cholesterol synthesis is highest. However, you may take atorvastatin anytime. (1)
Mnemonics for Atorvastatin name: A-sTAR-VAST-STATUE (a-tor-vast-stati-n)-----
Mnemonics for drug class: A-sTAR-VAST-STATUE right @ the Jail to be ready to beat the Heavy Metal Group up whenever they want to turn anyone into
criminals (
cholesterol)
Mnemonics for Atorvastatin use: A-sTAR-vastatin statue = always on the top = biggest drug with the biggest dosage for vasta-stin issues @ the vast-station
Mnemonics for Atorvastatin dosage: A-sTAR-VAST-STAT-in have seen it all => must be super good in order to deal with his sandwich age, i.e. 40 y/o (the age when you have to take care of both of your young kids & your elderly parents) and go double that 80!!!
Mnemonics for timing: at or anytime (atorvastatin)
 |
| A-sTAr-VAST-STAT-ue (Atorvastatin) |
References:
(1)https://books.google.com/books?id=3bjMBQAAQBAJ&pg=PA52&lpg=PA52&dq=atorvastatin+mnemonics&source=bl&ots=CRVSW5L4Gj&sig=Ep7JbQO8Ab8oanNr6K_PnD6pJ68&hl=en&sa=X&ved=0ahUKEwjg3tOhoJzMAhVOxGMKHY22CVYQ6AEIMzAE#v=onepage&q=atorvastatin%20mnemonics&f=false
Add-all = Add+er+all = dextro+amphetamine+amphetamine
mech.: effects on all adrenergic receptors (alpha & beta) => release NorEpi & Dopamine => Scheduled II => cautioned in drug dependence & ETOH patients
Dextro-Amphetamine = to the right - amphetamine
Dex-Edrine = dextro-epinephrine (=> affects all adrenergic receptors = alpha, beta)
methylphenidate has a date @ the concert
mech.: effects on all adrenergic receptors (alpha & beta) => release NorEpi & Dopamine => Scheduled II => cautioned in drug dependence & ETOH patients
guava-face (guan-faci-ne)=> aggressive kids eating guava => less aggressive
Use: adjunct for aggressive behavior, non-CNS stimulant
Place in therapy: non-CNS stimulant for ADHD, not as effective as a monotherapy compared with CNS stimulant
Mnemonics for bupropion: butt-prop to get your attention
Avoid: in pts w/ seizures
Use: Good for pts/ with depression & ADHD (depressed pts go party where there's lots of butt-prop which make them less depressed and the butt-prop got their attention)
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| butt-prop-ion => Bu-prop to get your attention |
-oxetine root word BUT NOT a SSRIs
Place in therapy: Non-CNS stimulant (NOT as effective as monotherapy compared w/ CNS stimulants)
Mnemonics:
strattera
straightens up these kids' improper behaviors. (1)
==> Wonder Me's mnemonics: oxygen tubing needs to be straighten => cannot be kinked to be used effectively on these kids.
 |
Atom Oxygen = Atom-Oxytine
|
 |
| Oxygen tank = Oxetine |
(1): https://books.google.com/books?id=uhSjCwAAQBAJ&pg=PA91&lpg=PA91&dq=oxetine+mnemonics&source=bl&ots=ZDbPjeAI7Z&sig=p60bSG8Xq0L2gUnJiJKRxhTZeMU&hl=en&sa=X&ved=0ahUKEwiutsiS7pTMAhVL6mMKHe8TBMQQ6AEIMjAD#v=onepage&q=oxetine%20mnemonics&f=false
-oxetine => anti-depressant (drug root)
Fluoxetine =>
flute ox serenade beer keeps
serotonin partying with her sarong
 |
| flute-ox-serenade (Flu-ox-etine) = Fluoxetine |
 |
| Sarong tony = Serotonin = the party girl (more of her, more fun = full of self-esteem) |
BBW: Vision loss
GABA derivative
Mnemonics for vigabatrin:
VirginGABA (
Vigabatrin)=> too innocent to see bad x stuff. Becuase VirginGABA is too innocent, bad guys (seizures) stay away from her because they don't want to touch the innocence.
Also, because VirginGABA is too innocent & vulnerable, lots of government programs needed to help VirginGABA such as the SHARE program.
the U
Penn Barbie (
Pento-
barbital) is the best to offer to these many seizures guys (refractory) who keeps frequenting the night club.
 |
| uPennBarbie for frequent (Pentobarbital for refractory seizures) |
 |
Bento-Barbie
 |
| Bento-Barbie = (Pentobarbital) |
|
Ethosuximide
Methsuximide
Use: absence seizure (first choice)
Meth-suximide = more toxic and less effective than ethosuximide
pent-house-barbital => refractory seizures (penthouse = as big as a factory)
Use: drug of
last choice for partial seizures => discuss thoroughly for all known risks before using
(Black box of fatal hepatoxic)
Drug name: Ezogabine/Retigabine
Drug class: misc. agents
Use: adjuct partial seizures only in refractory seizures when other agents have failed and benefits outweigh risks
BlackBox: vision loss
Mnemonics: Reti => Retina => threat to Retina (vision loss). Ezo => Ergot => threat to vision (so poisone unable to see). ====> Vision loss = refractory only = drug when other drugs failed
Retigabine => Reti grabs a pin causing the bad guys to lose vision. Thus, unable to detonate explosions they've been causing
Ezogabine => Ergot grabs a pin causing the bad guys to lose vision.Thus, unable to detonate explosions they've been causing
 |
Ergot => Ezogabine
|
Drug name: Perampanel
Drug class: misc. agent
Use: adjunct for partial
BlackBoxWarning: serious/life-threatening psych. & behavioral issues
Drug mnemonics: PER-Am-PANEL (going in front of a panel due to behavior issues. Think SARB panel which judges students with serious behavioral issues).
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| PER-am-PANEL (perampanel) for serious behavior issues which may include small explosions. Small explosions (partial) in school is considered serious and life-threatening. Therefore, it needs a panel. |
Drug name: Topiramate
Drug class: Misc. agents
Monitor:
- baseline serum bicarb & eGFR before therapy
- dose adjustment for renal impairment
Drug name mnemonics: Top-pirate. Top pirate => able to scare the bad guys away for seizure prevention. Pirate => water => renal. Water => put out explosions (seizures). Sea water => put out all kind of explosions (partial, generalized, Lennox Gastaut).
 |
Top-pirate = Topira-mate <=> all seizures as the primary
Sea <=> water = renal impairments & put out seizures |
Drug name: Valproic acid
Drug class: misc. agent
Use: generalized & partial seizures
Mech.: elevates GABA levels
Monitor: several drug-drug interaction levels => monitor drug levels
Drug name mnemonics:
Val, pro-earthquake fighter
Use mnemonics: Pro <=> primary for generalized & partial seizures
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