Diagnosis:
5 symptoms/2weeks 
- diminished interests in normal activity
- impaired concentration nearly every day
- sadness feelings

5 fingers (5 symptoms) in 2 hands (2 weeks)

Drug therapy:
- Antidepressants = 1/3 most commonly prescribed drug in US
Phases:

• - Acute phase = goal: remission
• - Continuation phase = after remission; goal: eliminate residual symptoms or prevent relapse
• - Maintenance phase = goal: prevent recurrence

- Terms:

• remission = absence of symptoms
• relapse = return of of symptoms within 6 mo. of remission
• recurrence = separate episode of depression

- Mech.:

• Increases NE
• Increases 5-HT
• Blocking reuptake
• Inhibit MAO
• Inhibit degradation

Anti-depressants classes:
1 - SSRIs (Selective Serotonin Reuptake Inhibitors)
2 - SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors)
3 - Serotonin Antagonists
4 - Atypical Antidepressants
5 - Tricyclic Antidepressants (TCAs)
6 - MonoAmine Oxidase Inhibitors (MAOIs)
7 - Misc
8 - Atypical Antipsychotics


Anti-depressants drugs: (drugs that keep party going)
1 - SSRIs (Selective Serotonin Reuptake Inhibitors) - (Sarah Throwing to keep party Going; keep drinking beers = inhibit reuptake away from Sarah)

• Fluoxetine (flying Ox Beers)
• Sertraline (Suds Lean Beers)
• Fluvoxamine
• Citalopram
• escitalopram
• vilazodone

Onset:
2 - SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors)
3 - Serotonin Antagonists

• Trazadone (Trance is Done on Sarah)
• nefazodone 

Onset:

• Onset: 4 weeks 

4 - Atypical Antidepressants
5 - Tricyclic Antidepressants (TCAs): --Tricycle races that keep the party going

• Amitriptyline ----Ami-TRIP-TYLINE -----(Amy rips to the line)
• Nortriptyline-----Nor-TRIP-TYLINE ------(Norton rips to the line)
• Protriptyline-----Pro-TRIP-TYLINE
• Imipramine ----- Imi-PRA-MINE-----------(He's singing 'I'm a praline)
• Desipramine----Desi-PRA-MINE-----------(Desi's singing 'Desi's a praline)
• Amoxapine
• Doxapin 

Onset: 4 weeks
BBW: suicidal ideation

6 - MonoAmine Oxidase Inhibitors (MAOIs) ---(Things that distract the bouncer. Rem: bouncer = MAO-Inhibitor)

• Tranylcypromine ---(Entrancing siren)
• Phenelzine-----------(Funnel for a beer bong)
• Isocarboxazid--------(Ice box with beer in it)

7 - Misc
8 - Atypical Antipsychotics

Praline

rips to the line