Wonder Me!
Diagnosis:
- Bipolar I: manic +/- depressive or mixed
- Biplar II: depression with hypomanic
- Cyclothymic: hypomania & mild depression fluctuations
- Bipolar NOS

Symptoms:
- Extreme opposite mood shifts
- Grandiosity or inflated self-esteem
- Talkativeness; flight of ideas
- Increased goal-directed

Drug Therapy:
1 - Lithium
2 - Anticonvulsants
3 - Anti-psychotic

Drug therapy names:
1 - Lithium (1st choice)

Tox.:

  • Monitor drug level. Target range: 0.6 - 1.5 mEq/L
  • Many drug drug interactions
  • Reduce dose in renal impairment
  • Salt (Na) affects lithium resorption in kidney

2 - Anticonvulsants (1st line therapy)

  • carbamazepine-------monitor drug level
  • lamotrigine ----------titrate slowly to minimize rash
  • valproic acid------monitor drug level
Tox.:
  • Many drug-drug interactions


3 - Anti-psychotic (1st line)
  • Risperidone---------Rispe-RIDONE
  • Ziprasidone---------Zipra-SIDONE
  • Lurasidone----------Lura-SIDONE
  • aripiprazole
  • asenapine ----------asen-APINE
  • olanzapine --------olanz-APINE
  • quetiapine ---------queti-APINE
  • cariprazine
Tox.:
weight gain, diabetes
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