Diagnosis:
- Bipolar I: manic +/- depressive or mixed
- Biplar II: depression with hypomanic
- Cyclothymic: hypomania & mild depression fluctuations
- Bipolar NOS
Symptoms:
- Extreme opposite mood shifts
- Grandiosity or inflated self-esteem
- Talkativeness; flight of ideas
- Increased goal-directed
Drug Therapy:
1 - Lithium
2 - Anticonvulsants
3 - Anti-psychotic
Drug therapy names:
1 - Lithium (1st choice)
Tox.:
2 - Anticonvulsants (1st line therapy)
3 - Anti-psychotic (1st line)
- Bipolar I: manic +/- depressive or mixed
- Biplar II: depression with hypomanic
- Cyclothymic: hypomania & mild depression fluctuations
- Bipolar NOS
Symptoms:
- Extreme opposite mood shifts
- Grandiosity or inflated self-esteem
- Talkativeness; flight of ideas
- Increased goal-directed
Drug Therapy:
1 - Lithium
2 - Anticonvulsants
3 - Anti-psychotic
Drug therapy names:
1 - Lithium (1st choice)
Tox.:
- Monitor drug level. Target range: 0.6 - 1.5 mEq/L
- Many drug drug interactions
- Reduce dose in renal impairment
- Salt (Na) affects lithium resorption in kidney
2 - Anticonvulsants (1st line therapy)
- carbamazepine-------monitor drug level
- lamotrigine ----------titrate slowly to minimize rash
- valproic acid------monitor drug level
Tox.:
- Many drug-drug interactions
3 - Anti-psychotic (1st line)
- Risperidone---------Rispe-RIDONE
- Ziprasidone---------Zipra-SIDONE
- Lurasidone----------Lura-SIDONE
- aripiprazole
- asenapine ----------asen-APINE
- olanzapine --------olanz-APINE
- quetiapine ---------queti-APINE
- cariprazine
Tox.:
weight gain, diabetes
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