Wonder Me!
Pathophys:

  • motor area of cerebral cortex damage
Causes:
  • spinal  injury
  • trauma
  • neuro-degenerative injury
  • dystonia
Symptoms:
  • muscle spasm
  • spasticity 

Drug therapy:
  • skeletal muscle relaxant
  • direct-acting anti-spasmodics
  • neuro-muscular blocking agents:
Drug names:
1 - Skeletal muscle relaxant:
  • baclofen ---- BACK-lo-pha^.n => relax ur back, let baclofen work for you
  • carisoprodol---Carries-all-professional=> no need to worry about anything => relax muscles, let them work
  • methocarbamol--Mentos-eaten-in-car-relaxes-kamol before seeing his date 
  • tizanidine---seeing-tarzan-makes-jane-relaxe


2 - Direct-acting anti-spasmodics:
  • OnabotulinumtoxinA => stop spasm. Don't give over 360units/3mo
  • Dantrolene  ----(denture-lion=frozen in scare => cannot move anymore, even tho before was shaking like crazy) ---100mg/4x/day 

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