Naming:
| -azoline | Antihistamines/local vasoconstrictors (antazoline type) | antazoline |
Use:
Nasal decongestant (temp. relief of nasal congestion due to rhinitis or cold (1))
sprays preferred over drops due to less systemic absoprtion (1)
should not be used over 3 days due to risk of rebound congestion (1)
Mnemonics:
Oxy- = oxygen
-azoline = aline = Et j'ai pleuré, pleuré, oh! j'avais trop de peine (AND I CRIED, CRIED, OH! I WAS SO SAD!)
=> crie = runny nose
z=> 2
az=> alpha2 - alfafa stabbing nose = stops bleeding
Mnemonics:
Oxy- = oxygen
-azoline = aline = Et j'ai pleuré, pleuré, oh! j'avais trop de peine (AND I CRIED, CRIED, OH! I WAS SO SAD!)
=> crie = runny nose
z=> 2
az=> alpha2 - alfafa stabbing nose = stops bleeding
 |
| Az = A2 (as in -Azoline) |
Receptors/Why it works:
Alpha 2 (peripherally)
=> acts on the arterioles of the nasal mucosa
=> causes constriction
=> decreases blood flow & nasal congestion
=> acts on the arterioles of the nasal mucosa
=> causes constriction
=> decreases blood flow & nasal congestion
(1) https://books.google.com/books?id=0rIiBlmpTD4C&pg=PA294&dq=oxymetazoline&hl=en&sa=X&ved=0ahUKEwi-yd_Fnv7LAhVS72MKHXxTAaIQ6AEIRTAI#v=onepage&q=oxymetazoline&f=false
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