PPT Indication: prophylaxis & treatment for chronic constipation
Text: Glucose levels should be monitored in diabetic pts who ingest oral sorbitol
(Wonder Me's explanation: Sorbitol is a form of sugar alcohol that does not cause much increase in blood sugar as sucrose, regular sugar does but still causes an increase in blood sugar.)
Medscape dosage: 0.5-2 mL/kg up to 50 mL of 70% solution PO qDay/QID
Mnemonics: Sorbitol the sobbing one!
Sorbitol sobbing so much while sitting in the jammed car (constipation) that her crying makes a flood moving the car. Sorbitol the sobbing one. Of course, if she cries (oral one), it takes a long time to really accumulate enough to produce relief of jammed cars (constipation). However, if a lot of her coming in from the end of the tunnel (anus - enema), it's a lot! Quick relief!
Medscape:
Text: Glucose levels should be monitored in diabetic pts who ingest oral sorbitol
(Wonder Me's explanation: Sorbitol is a form of sugar alcohol that does not cause much increase in blood sugar as sucrose, regular sugar does but still causes an increase in blood sugar.)
Medscape dosage: 0.5-2 mL/kg up to 50 mL of 70% solution PO qDay/QID
120 mL of 25-30% solution PR qDay
Mnemonics: Sorbitol the sobbing one!
Sorbitol sobbing so much while sitting in the jammed car (constipation) that her crying makes a flood moving the car. Sorbitol the sobbing one. Of course, if she cries (oral one), it takes a long time to really accumulate enough to produce relief of jammed cars (constipation). However, if a lot of her coming in from the end of the tunnel (anus - enema), it's a lot! Quick relief!
Medscape:
Bioavailability: poor absorption (oral and rectal)
Metabolism: mainly in the liver to fructose
Mechanism of Action: Polyalcoholic sugar with hyper osmotic effects
http://reference.medscape.com/drug/sorbitol-342033#10
Wiki:
Sorbitol is found in some dried fruits and may contribute to the laxative effects of prunes.
Sorbitol can be used as a non-stimulant laxative via an oral suspension or enema. As with other sugar alcohols, gastrointestinal distress may result when food products that contain sorbitol are consumed. Sorbitol exerts its laxative effect by drawing water into the large intestine, thereby stimulating bowel movements.
https://en.wikipedia.org/wiki/Sorbitol
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