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Thalessemia is a defective globin (as in heme-o-globin) disorder.
There are 2 types of globins in a rbc: alpha & beta globin.

Thalasemia is a genetic condition where the body either does not make enough hemoglobin or the hemoglobin it makes is not normal. Hemoglobin is a component of red blood cells that helps spread oxygen throughout the body. To make hemoglobin the body needs both alpha-globin and beta-globin.
Alpha thalasemia occurs if there are problems with some or all of the alph-globin genes. Beta thalasemia occurs when there are problems with one or both of the beta-globin genes.
Here is a link to an article about thalassemia with lots of info.
http://www.webmd.com/a-to-z-guides/thalassemia-topic-overview



Read more @ http://www.merckmanuals.com/professional/hematology-and-oncology/anemias-caused-by-hemolysis/thalassemias
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