Calcium channel blockers
Class Summary
Calcium channel blockers reduce the amplitude of contractions. In nutcracker esophagus, calcium channel blockers effectively reduce the amplitude of contractions, but chest pain often is not reduced. Whether calcium channel blockers decrease the force of contraction of muscle or decrease the underlying stimulus is unknown.
Diltiazem (Cardizem, Cartia XT, Dilacor XR, Diltzac, Tiazac, Diltia XT)
Diltiazem is FDA approved for hypertension, vasospastic angina, and chronic stable angina. It decreases calcium ion flux across cell membranes in smooth muscle, thereby relaxing vascular smooth muscle.
Alarm Symptoms (for dyspepsia / GERD) Mnemonic
ALARM Symptoms
Anaemia (iron deficiency)
Loss of weight
Anorexia
Recent onset of progressive symptoms
Melaena / haematemesis
Swallowing difficulty
Anaemia (iron deficiency)
Loss of weight
Anorexia
Recent onset of progressive symptoms
Melaena / haematemesis
Swallowing difficulty
If dyspepsia and either >55yrs or ALARM Symptoms then ENDOSCOPY
Source: http://med-mnemonics.blogspot.com/2015/03/alarm-symptoms-for-dyspepsia-gerd.html
Source: http://med-mnemonics.blogspot.com/2015/03/alarm-symptoms-for-dyspepsia-gerd.html
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