http://microbeonline.com/difference-staphylococcus-streptococcus/

Staphylococcus and Streptococcus are two most common pathogenic gram positive cocci of medical importance.  They share some of the important properties.

Common characteristics shared by of these gram positive cocci are:

• Non motile,
• Non Sporing,
• Facultative anaerobes

Characteristic	Staphyloccus	Streptococcus
Shape	Gram positive cocci in clusters (grape-like) becausecell division occurs in various directions on multiple axes. Gram positive cocci in pairs, tetrads, short chains also seen.	Gram Positive cocci in pairs or short chains (Cell division occurs in single axis)
Catalase Test (Most Important test to differentiate Staph from Strep)	Positive (Presence of catalase enzyme)	Negative
Growth Requirement	Not fastidious (Does not need enriched media)	Fastidious (needs enriched media).
Hemolysis	No hemolysis or beta hemolysis	Either alpha, or beta or gamma hemolysis (Hemolysis can be helpful to differentiate species of Streptococcus)
Common habitat	Mostly skin, anterior nares	Mainly mouth and respiratory tract
Common Diseases	Pneumonia, Meningitis, osteomyelitis, acute endocarditis, septic arthritis, Surgical Site Infection, Wound infection etc.	Pneumonia, Sore throat, Wound Infection, Necrotizing fascitis,  Scarlet fever, Rheumatic fever, Acute post-streptococcal glomerulonephritis
Most Pathogenic species	Staphylococcus aureus Staphyloccus saprophyticus (in female)	Streptoccus pneumoniae Streptoccus pyogens Streptococcus agalactiae
Useful diagnostic tests	Catalase Test Coagulase Test Novobiocin sensitivity test	Catalase TestBacitracin Sensitivity Test (S. pyogens) Optochin Sensitivity Test (S. pneumoniae) Bile solubility Test (S. pneumoniae) CAMPT Test (S. agalactiae)