Definition:
GPCR are agonist that binds to receptor => cascading of GDP to become GTP

Example: Adreno-receptors are G-Protein Coupled Receptors (1). Wonder Me! mnemonics: think adrenergic = super energy = cascading of GDP-GTP. GDP-GTP think G think coupled


Clinical example: (1)

- Many drugs are alpha agonist or alpha antagonist
- Alpha-1 adrenergic agonist = Nor-adrenaline, Phenylephrine
- Alpha-1 blockers = Phenoxybenzamine
- Alpha-2 agonist = Clonidine
- Alpha-2 blockers = Phentolamine
- Beta-1 agonist = dobutamine
- Beta-1 blockers = propanolol
- Beta-2 agonist = Albuterol
- Beta-2 blockers = propanolol