Group class: Tricyclic compounds
Meds: carbamezepine, oxcarbazepine, eslicarbazepine
Drug root: CARBA-ZEPINE as in CARBAmaZEPINE, oxCARBAZEPINE, esliCARBAZEPINE
Mnemonics for name: Car-Bombz-A-Pin (the car bombz was deactivated with A Pin) - the car bombz (carba-car bombz) must be activated by the pin (zepine)
Think CAR => Cyclic => Tri-Cyclic
Mech.: Unknown for sure. However, it's proposed that it's similar to Phenytoin/Fos-phenytoin which are to modulate Sodium channel.
Mnemonics for mech.: Car-Bombz-A-Pin is kinda similar to Funny-Toes-In ....
Black box warning: Fatal derm rxns (SJS/TEN) ===> Test for HLA-B*1502 prior to therapy
Mnemonics for Black Box Warning: Just think Car-Bombz (Carba-zepine) is much bigger and thus much lethal than Funny-toes-in (Phenytoin) => if not careful, it could cause severe burn => SJS/TEN
Meds: carbamezepine, oxcarbazepine, eslicarbazepine
DRUG NAME
Drug root: CARBA-ZEPINE as in CARBAmaZEPINE, oxCARBAZEPINE, esliCARBAZEPINE
Mnemonics for name: Car-Bombz-A-Pin (the car bombz was deactivated with A Pin) - the car bombz (carba-car bombz) must be activated by the pin (zepine)
Think CAR => Cyclic => Tri-Cyclic
MECHANISM
Mech.: Unknown for sure. However, it's proposed that it's similar to Phenytoin/Fos-phenytoin which are to modulate Sodium channel.
Mnemonics for mech.: Car-Bombz-A-Pin is kinda similar to Funny-Toes-In ....
BLACK BOX WARNING
Black box warning: Fatal derm rxns (SJS/TEN) ===> Test for HLA-B*1502 prior to therapy
Mnemonics for Black Box Warning: Just think Car-Bombz (Carba-zepine) is much bigger and thus much lethal than Funny-toes-in (Phenytoin) => if not careful, it could cause severe burn => SJS/TEN
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