Wonder Me!
Group class: Tricyclic compounds
Meds: carbamezepine, oxcarbazepine, eslicarbazepine

DRUG NAME

Drug root: CARBA-ZEPINE as in CARBAmaZEPINE, oxCARBAZEPINE, esliCARBAZEPINE

Mnemonics for name: Car-Bombz-A-Pin (the car bombz was deactivated with A Pin) - the car bombz  (carba-car bombz) must be activated by the pin (zepine)

Think CAR => Cyclic => Tri-Cyclic

MECHANISM

Mech.: Unknown for sure. However, it's proposed that it's similar to Phenytoin/Fos-phenytoin which are to modulate Sodium channel.

Mnemonics for mech.: Car-Bombz-A-Pin is kinda similar to Funny-Toes-In ....


BLACK BOX WARNING

Black box warning: Fatal derm rxns (SJS/TEN) ===> Test for HLA-B*1502 prior to therapy

Mnemonics for Black Box Warning: Just think Car-Bombz (Carba-zepine) is much bigger and thus much lethal than Funny-toes-in (Phenytoin) => if not careful, it could cause severe burn => SJS/TEN






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