"The tremor often spreads to the other side of the body as the disease progresses, but will remain most obvious on the side of the body where it first started.

A few more points on tremors include:

• usually occur at rest, may occur at any time
• may become severe enough to interfere with activities
• may be worse when tired, excited, or stressed
• finger-thumb rubbing (*pill-rolling tremor) may be present

*NOTE: ("Pill-rolling" is seen especially in the hands; this is fairly unique to Parkinson's disease. The term refers to the motion that a pharmacist uses to align a handful of pills before placing them in a bottle or, possibly, the motion used to roll a marble between the thumb and forefinger. Eventually the tremor becomes more generalized.)"