-abine | (see -arabine, -citabine) | decitabine |
-ac | Anti-inflammatory agents (acetic acid derivatives) | bromfenac; dexpemedolac |
-acetam | See -racetam | |
-actide | Synthetic corticotropins | seractide |
-adol or -aldol- | Analgesics (mixed opiate receptor agonists/ antagonists) | tazadolene; spiradolene; levonantradol |
-adox | Antibacterials (quinoline dioxide derivatives) | carbadox |
-afenone | Antiarrhythmics (propafenone derivatives) | alprafenone; diprafenone |
-afil | PDE5 inhibitors | tadalafil |
-aj- | Antiarrhythmics (ajmaline derivatives) | lorajmine |
-aldrate | Antacid aluminum salts | magaldrate |
-algron | Alpha1 - and alpha2 - adrenoreceptor agonists | dabuzalgron |
-alol | Combined alpha and beta blockers | labetalol; medroxalol |
-amivir | (see -vir) | |
-ampa | Ionotropic non-NMDA glutamate receptors (AMPA and/or KA receptors) | |
subgroups: |
-ampanel | Ionotropic non-NMDA glutamate receptors (AMPA and/or KA receptors); antagonists | becampanel |
-ampator | Ionotropic non-NMDA glutamate receptors (AMPA and/or KA receptors); modulators | forampator |
-andr- | Androgens | nandrolone |
-anib | Angiogenesis inhibitors | semaxanib |
-anserin | Serotonin 5-HT2 receptor antagonists | altanserin; tropanserin; adatanserin |
-antel | Anthelmintics (undefined group) | carbantel |
-antrone | Antineoplastics; anthraquinone derivatives | pixantrone |
-apsel | P-selectin antagonists | torapsel |
-arabine | Antineoplastics (arabinofuranosyl derivatives) | fazarabine; fludarabine |
aril-, -aril, -aril- | Antiviral (arildone derivatives) | pleconaril; arildone; fosarilate |
-arit | Antirheumatics (lobenzarit type) | lobenzarit; clobuzarit |
-arol | Anticoagulants (dicumarol type) | dicumarol |
-arone | Antiarrhythmics | amiodarone; dronedarone |
-arot- | Arotinoids | etarotene; sumarotene; tazarotene |
subgroup: |
-arotene | Arotinoid derivatives | bexarotene; linarotene; tazarotene |
arte- | Antimalarials (artemisin derivatives) | arteflene |
-ase | Enzymes | alglucerase; dornase alfa |
subgroups: |
-dismase | Enzymes; superoxide dismutase activity (exception: orgotein) | sudismase |
-teplase | Enzymes; tissue-type plasminogen activators | alteplase; duteplase; silteplase |
-uplase | Enzymes; urokinase-type plasminogen activators | saruplase; nasaruplase |
-ast | Antiasthmatics/antiallergics (not acting primarily as antihistamines; leukotriene biosynthesis inhibitors) | |
subgroups: |
-lukast | Antiasthmatics/antiallergics; leukotriene receptor antagonists | cinalukast; pobilukast |
-milast | Antiasthmatics/antiallergics; type IV phosphodiesterase inhibitors | piclamilast |
-trodast | Antiasthmatics/antiallergics; thromboxane A2 receptor antagonists | seratrodast |
-zolast | Antiasthmatics/antiallergics; benzoxazole derivatives | eclazolast; ontazolast |
-tegr- | Antiasthmatics/antiallergics; integrin antagonists | valategrast |
-astine | Antihistaminics (histamine-H1 receptor antagonists) | ebastine |
-(a)tadine | Tricyclic histaminic-H1 receptor antagonists, loratadine derivatives | desloratadine; rupatadine; somantadine |
-atadine | Tricyclic antiasthmatics | olopatadine; loratadine |
-axine | Antianxiety, antidepressant inhibitor of norepinephrine and dopamine re-uptake | |
subgroup: |
-(f)axine | | radafaxine |
-azenil | Benzodiazepine receptor agonists/antagonists | bretazenil; flumazenil |
-azepam | Antianxiety agents (diazepam type) | lorazepam |
-azepide | Cholecystokinin receptor antagonists | devazepide |
-azocine | Narcotic antagonists/agonists (6,7-benzomorphan derivatives) | quadazocine; ketazocine |
-azoline | Antihistamines/local vasoconstrictors (antazoline type) | antazoline |
-azosin | Antihypertensives (prazosin type) | doxazosin |
-bactam | Beta-lactamase inhibitors | sulbactam |
-bamate | Tranquilizers/antiepileptics (propanediol and pentanediol groups) | meprobamate; felbamate |
-barb or -barb | Barbituric acid derivatives | phenobarbital; secobarbital; eterobarb |
-begron | Beta 3 adrenoreceptor agonist | talibegron |
-bendazole | Anthelmintics (tibendazole type) | cambendazole |
-berel | Beta estrogen receptor agonist | prinaberel |
-bersat | Anticonvulsants; antimigraine (benzoylamino-benzpyran derivatives) | carabersat; tidembersat |
bol- or -bol- | Anabolic steroids | bolandiol; mibolerone |
-bufen | Non-steroidal anti-inflammatory agents, fenbufen derivatives | indobufen |
-bulin | Antineoplastics (mitotic inhibitors; tubulin binders) | mivobulin |
-butan | Antiseptics (dapabutan type) | dapabutan; lopobutan |
-butazone | Anti-inflammatory analgesics (phenylbutazone type) | mofebutazone |
-caine | Local anesthetics | dibucaine |
calci- or -calci- | Vitamin D analogues | calcipotriene; tacalcitol |
-camra | Antivirals (intracellular adhesion molecules, icam-1 derivatives) | tremacamra |
-camsule | Camphorsulfonic acid derivatives used as UVA sunscreens | ecamsule |
-casan | Caspase (interleukin –1b) converting enzyme inhibitors | pralnacasan |
-caserin | Serotonin receptor agonists, primarily 5-HT2 | lorcaserin; vabicaserin |
-castat | (see -stat) | |
-carbef | Antibiotics (carbacephem derivatives) | loracarbef |
-catib | Cathespin inhibitors | balicatib |
-cavir | (see -vir) | |
cef- | Cephalosporins | cefazolin |
-cept | Receptor molecules, native or modified ( a preceding infix should designate the target) | alvircept |
subgroups: |
-co- | Receptor molecules, native or modified;complement receptors | mirococept |
-facept | Receptor molecules, native or modified;lymphocyte function-associated with antigen 3 (LFA) receptor | alefacept |
-farcept | Receptor molecules, native or modified; interferon receptors | pifarcept |
-lefacept | Receptor molecules, native or modified; lymphocyte function-associated antigen 3 | alefacept |
-nercept | Receptor molecules, native or modified; tumor necrosis factor receptors | lenercept |
-vircept | Receptor molecules, native or modified; antiviral receptors | alvircept |
-cet | Receptors (small molecule) | |
subgroup: |
-calcet | Receptors (small molecule); calcium | tecalcet |
-cetrapib | Cholesterol ester transfer protein inhibitors | torcetrapib |
-cic | Hepatoprotectives (timonacic type) | limazocic |
-ciclib | Cyclin dependent kinase inhibitors | seliciclib |
-ciclovir | (see -vir) | |
-cidib | Cyclin dependent kinase inhibitor | alvocidib |
-cidin | Natural antibiotics (undefined group) | gramicidin |
-ciguat | Guanaline cyclase activator | ataciguat; atriciguat |
-cillin | Penicillins | ampicillin |
-citabine | Nucleoside antiviral or antineoplastic agents, cytarabine or azarabine derivatives | gemcitabine; fiacitabine; zalcitabine |
-clidine | Muscarinic agonists (various indications) | vedaclidine; talsaclidine |
-clone | Hypnotics/tranquilizers (zopiclone type) | pagoclone |
-cog | Blood coagulation factors | |
subgroups: |
-eptacog | Blood coagulation factors; blood coagulation factor VII | eptacog alfa (activated) |
-nonacog | Blood coagulation factors; blood coagulation factor IX | nonacog alfa |
-octocog | Blood coagulation factors; blood coagulation factor VIII | moroctocog alfa; octocog alfa |
-cogin | Blood coagulation cascade inhibitor | tifacogin |
-conazole | Systemic antifungals (miconazole type) | fluconazole; oxiconazole |
-cort- | Cortisone derivatives | hydrocortisone |
-coxib | Cyclooxygenase-2 inhibitors | celecoxib; parecoxib; valdecoxib |
-cridar | (see -dar) | |
-crinat | Diuretics (ethacrynic acid derivatives) | brocrinat |
-crine | Acridine derivatives | amsacrine; quinacrine |
-cromil | Antiallergics (cromoglicic acid derivatives) | nedocromil |
-curium (also -curonium) | Neuromuscular blocking agents (quaternary ammonium compounds) | atracurium; alcuronium; pipecuronium |
-cycline | Antibiotics (tetracycline derivatives) | minocycline |
-dan | Positive inotropic agents (pimobendan type) | prinoxodan; indolidan |
-dapsone | Antimycobacterials (diaminodiphenylsulfone derivatives) | acedapsone |
-dar | Multidrug resistance inhibitors | |
subgroups: |
-cridar | Multidrug resistance inhibitors;acridine carboxamide derivatives | elacridar |
-icodar | Multidrug resistance inhibitors;pipecolic acid derivatives | biricodar |
-quidar | Multidrug resistance inhibitors; quinoline derivatives | lamiquidar; zozuquidar |
-spodar | Multidrug resistance inhibitors; ciclosporin D derivatives | valspodar |
-denoson | Adenosine A receptor agonists | tecadenoson; binodenoson |
-dermin | (see -ermin) | |
dil-, -dil- or -dil | Vasodilators (undefined group) | fostedil |
-dipine | Phenylpyridine vasodilators (nifedipine type) | darodipine; felodipine |
-dismase | (see -ase) | |
-distim | (see -stim) | |
-ditan | Antimigraine (5-HT1 receptor agonists) | alniditan |
-dopa | Dopamine receptor agonists | levodopa |
-dore | Dopamine D2D3 receptor modulators | aplindore fumarate |
-dotin | Synthetic analogs of the dolastatin series | tasidotin HCl |
-dralazine | Antihypertensives (hydrazine-phthalazines) | hydralazine; endralazine |
-dronate | Calcium metabolism regulators | etidronate; tiludronate |
-dutant | (see -tant) | |
-ectedin | Ecteinascodin derivatives | monectedin |
-ectin | Antiparasitics (ivermectin type) | doramectin; moxidectin |
-elestat | (see -stat) | |
-elvakin | (see -kin) | |
-emcinal | Erythromycin derivatives lacking antibiotic activity | mitemcinal |
-entan | Endothelin receptor antagonists | bosentan |
-eptacog | (see -cog) | |
-eptakin | (see -kin) | |
-erg- | Ergot alkaloid derivatives | pergolide |
-eridine | Analgesics (meperidine type) | anileridine |
-ermin | Growth factors | |
subgroups: |
-bermin | Growth factors; vascular endothelial growth factors | telbermin |
-dermin | Growth factors; epidermal growth factors | murodermin |
-fermin | Growth factors; fibroblast growth factors | ersofermin |
-nermin | Growth factors; tumor necrosis factors | sonermin; tasonermin |
-plermin | Growth factors; platelet derived growth factors | becaplermin |
-sermin | Growth factors; insulin-like growth factors | mecasermin |
-termin | Growth factors; transforming growth factors | cetermin |
sub subgroups: |
-otermin | Growth factors; bone morphogenetic proteins | dibotermin alfa |
estr- or -estr- | Estrogens | estrone; fenestrel |
subgroups: |
-estrant | Estrogen antagonists | fulvestrant |
-etanide | Diuretics (piretanide type) | bumetanide |
-exakin | (see -kin) | |
-ezolid | Oxazolidinone antibacterials | eperezolid; linezolid |
-farnib | Farnesyl transferase inhibitor | tipifarnib |
-fenamate | "fenamic acid" ester or salt derivatives | etofenamate |
-fenamic acid | Anti-inflammatory agents (anthranilic acid derivatives) | flufenamic acid |
-fenin | Diagnostic aids ((phenylcarbamoyl)methyl iminodiacetic acid derivatives) | arclofenin |
-fenine | Analgesics (fenamic acid subgroup) | floctafenine |
-fentanil | Narcotic analgesics (fentanyl derivatives) | alfentanil; mirfentanil; brifentanil |
-fentrine | Phosphodiesterase inhibitor | pumafentrine |
-fermin | (see -ermin) | |
-fetamin(e) | Amfetamine derivatives | levmetamfetamine |
-fiban | Fibrinogen receptor antagonists (glycoprotein IIb/IIIa receptor antagonists) | lamifiban; tirofiban |
-fibatide | (see -tide) | |
-fibrate | Antihyperlipidemics (clofibrate type) | bezafibrate |
-filcon | Hydrophilic contact lens materials | alphafilcon A; xylofilcon A; mipafilcon A |
-fingol | Sphingosine derivatives | cedefingol; safingol |
-flapon | 5-lipoxygenase-activating protein (FLAP) inhibitors | quiflapon |
-flurane | General inhalation anesthetics (halogenated alkane derivatives) | enflurane |
-fo- | Phosphoro-derivatives | adefovir |
-focon | Hydrophobic contact lens materials | trifocon A; pasifocon B; satafoconA |
-formin | Hypoglycemics (phenformin type) | buformin |
-fradil | Calcium channel blockers acting as vasodilators | mibefradil |
-fulven | Antineoplastic, acylfulven derivatives | viridofulven |
-fungin | Antifungal antibiotics (undefined group) | kalafungin |
-fylline | Theophylline derivatives | enprofylline; bamifylline; cipamfylline |
-gab- | Gabamimetics | fengabine |
gado- | Gadolinium derivatives (principally for diagnostic use) | gadodiamide; gadoteridol;gadobenate |
-gapil | Neuronal apoptosis inhibitors; GAPDH | omigapil |
-ganan | Antimicrobial, bactericidal permeability increasing polypeptide | iseganan; pexiganan |
-gatran | Thrombin inhibitors (argatroban type) | efegatran |
-gest- | Progestins | megestrol |
-giline | MAO inhibitors, type B | selegiline |
-gillin | Antibiotics (Aspergillus strains) | mitogillin |
gli- | Antihyperglycemics | gliflumide |
-gliptin | Antihyperglycemics; dipeptidyl aminopeptidase-IV inhibitors | vildagliptin |
-glitazar | Antihyperglycemics; PPAR agonists (not thiazolidene derivatives) | farglitizar |
-glitazone | Antihyperglycemics; PPST agonists (thiazolidene derivatives) | ciglitazone; rosiglitazone |
-glumide | CCK antagonists, antiulcer, anxiolytic agent | amiglumide; itriglumide |
-golix | GnRH receptor antagonists (nonpeptide) | rupugolix |
-gosivir | (see -vir) | |
-gramostim | (see -stim) | |
-grastim | (see -stim) | |
-grel- or -grel | Platelet aggregation inhibitors (undefined group) | itazigrel; dimetagrel; furegrelate |
guan- | Antihypertensives (guanidine derivatives) | guanoctine |
-ibat | Ileal bile acid transport inhibitor | barixibat |
-icam | Anti-inflammatory agents (isoxicam type) | enolicam; tenoxicam |
-icodar | (see -dar) | |
-ifen(e) | Antiestrogens of the clomifene and tamoxifen groups | nitromifene; raloxifene; droloxifene |
-ilide | Class III antiarrhythmic agents | ibutilide; risotilide; dofetilide |
-imepodib | Inosine monophosphate dehydrogenase inhibitors | merimepodib |
-imex | Immunostimulants | forfenimex; roquinimex; ubenimex |
-imibe- | Antihyperlipidaemics, acyl CoA: cholesterol acyltransferase (ACAT) inhibitors | eldacimibe; avasimibe; pactimibe |
-imod | Immunomodulators | ivarimod; pidotimod |
subgroup: |
-mapimod | Immunomodulators; mitogen-activated protein (MAP) kinase inhibitors | dormapimod |
-imus | Immunosuppressives | tacrolimus; napirimus; gusperimus; sirolimus |
io- | Iodine-containing contrast media | iodamide |
-irudin | Anticoagulants (hirudin type) | desirudin |
-isant | Histamine H3 receptor antagonists | cipralisant |
-isomide | Antiarrhythmics (disopyramide derivatives) | bidisomide |
-ium (also -onium) | Quaternary ammonium derivatives | clidinium; disiquonium; polixetonium |
-ixafor | CXCR4 antagonists | plerixifor |
-kacin | Antibiotics obtained from Streptomyces kanamyceticus (related to kanamycin) | amikacin |
-kalant | Potassium channel antagonists | almokalant; terikalant |
-kalim | Potassium channel agonists | cromakalim; aprikalim |
-kalner | Opener of large conductance calcium-activated (maxi-k) K+ channels | flindokalner |
-kef- | Enkephalin agonists (various indications) | metkephamide; casokefamide |
-kin | Interleukin type substances | |
subgroups: |
-decakin | Interleukin type substances; interleukin-10 analogues and derivatives | ilodecakin |
-dodekin | Interleukin type substances; interleukin-12 analogues and derivatives | edodekin alfa |
-elvekin | Interleukin type substances; interleukin 11 analogues and derivatives | oprelvekin |
-eptakin | Interleukin type substances; interleukin 7 analogues and derivatives | |
-exakin | Interleukin type substances; interleukin 6 analogues and derivatives | atexakin alfa |
-leukin | Interleukin type substances; interleukin 2 analogues and derivatives | teceleukin; aldesleukin |
-nakin | Interleukin 1 analogues and derivatives | |
sub subgroups: |
-onakin | Interleukin 1 analogues and derivatives; interleukin 1-a analogues and derivatives | pitonakin |
-benakin | Interleukin 1 analogues and derivatives; iinterleukin 1-b analogues and derivatives | mobenakin |
-nonakin | Interleukin 1 analogues and derivatives; iinterleukin 9 analogues and derivatives | |
-octakin | Interleukin 1 analogues and derivatives; iinterleukin 8 analogues and derivatives | emoctakin |
-penkin | Interleukin 1 analogues and derivatives; iinterleukin 5 analogues and derivatives | |
-trakin | Interleukin 1 analogues and derivatives; iinterleukin 4 analogues and derivatives | binetrakin |
-kinra | Interleukin receptor antagonists | |
subgroup: |
-nakinra | Interleukin receptor antagonists; interleukin 1 (IL-1) receptor antagonists | anakinra |
-kiren | Renin inhibitors | ditekiren; terlakiren; zankiren |
-lazad | Lipid peroxidation inhibitors | tirilazad |
-leptin | Leptin derivatives | metreleptin |
-leukin | (see -kin) | |
-lind | Pro-apoptotic cGMP phosphodiesterase inhibitors | ractalind; dractalind |
subgroup: |
-sulind | Pro-apoptotic cGMP phosphodiesterase inhibitors; antineoplastics, sulindac metabolites | exisulind |
-lipim | Lipoprotein lipase activators | ibrolipim |
-locib | Antineoplastics that inhibit the formation of 5-LO, LTB4, LTC4, and thromboxane B2 (TxB2); and Activate PPARg nuclear receptors | etalocib |
-lubant | Leukotriene receptor antagonists (treatment of inflammatory skin disorders) | ticolubant |
-lukast | (see -ast) | |
-lutamide | Antiandrogens | bicalutamide; flutamide |
-lutril | Neutral endopeptidase inhibitors possessing additional endothelin converting enzyme inhibitory activity | daglutril |
-mab | Monoclonal antibodies | imciromab; abciximab; capromab; dacliximab; detumomab; enlimomab |
subgroups: |
-axo- | Monoclonal antibodies; rat-murine hybrid antibodies | |
-les- | Monoclonal antibodies; infix for inflammatory/infectious lesions | |
-toxa- | Monoclonal antibodies; toxin as a target | urtoxazumab |
-mantadine or -mantine | Antivirals/antiparkinsonians (adamantane derivatives) | rimantadine; dopamantine |
-mastat | (see -stat) | |
-meline | Cholinergic agonists (arecoline derivatives used in treatment of Alzheimer's disease) | xanomeline |
-melteon | Selective melatonin receptor agonist | ramelteon |
-mer | Polymers | cadexomer; carbetimer |
-mesine | Sigma receptor ligands | igmesine; panamesine |
-mestane | Antineoplastics (aromatase inhibitors) | plomestane |
-metacin | Anti-inflammatory agents (indomethacin type) | zidometacin |
-micin | Antibiotics (Micromonospora strains) | maduramicin; gentamicin |
-monam | Monobactam antibiotics | gloximonam; oximonam; tigemonam |
-morelin | (see -relin) | |
-moren | Non-peptidic growth hormone secretagogues | ibutamoren |
-mostim | (see -stim) | |
-motine | Antivirals (quinoline derivatives) | famotine |
-moxin | Monoamine oxidase inhibitors (hydrazine derivatives) | benmoxin; domoxin |
-mulin | Antibacterials, pleuromulin derivatives | retapamulin |
-multin | Mucosal tolerance inductors | ismomultin |
-mustine | Antineoplastics (chloroethylamine derivatives) | carmustine |
-mycin | Antibiotics (Streptomyces strains) | lincomycin |
nab- or -nab- | Cannabinol derivatives | nabazenil; dronabinol |
-nakalant | Mixed sodium/potassium channel blockers | vernakalant |
-nakin | (see -kin) | |
nal- | Narcotic agonists/antagonists (normorphine type) | nalmefene |
-navir | (see -vir) | |
-nercept | (see -cept) | |
-nermin | (see -ermin) | |
-nertant | Neurotensin receptor antagonists | reminertant |
-nesib | Kinesin inhibitors | ispinesib |
-netant | (see -tant) | |
-neurin | Neurotensin receptor antagonists; neurotropins | abrineurin |
-nicline | Nicotinic acetylcholine receptor partial agonists/agonists nonsteroidal anti-inflammatory agents (tenidap | altinicline |
-nidap | Nonsteroidal anti-inflammatory agents (tenidap type) | ilonidap; tenidap |
-nidazole | Antiprotozoal substances (metronidazole type) | tinidazole |
nifur- | 5-nitrofuran derivatives | nifuratel; nifuratrone |
-nil | Benzodiazepine receptor antagonists/agonists | |
subgroups: |
-punil | Mitochondrial benzodiazepine receptor (MBR) selective, partial, or inverse agonists (purine derivatives) | emapunil |
-quinil | Benzodiazepine receptor agonists, also partial or inverse (quinoline derivatives) | lirequinil |
-nixin | Anti-inflammatory agents (anilinonicotinic acid derivatives) | clonixin |
-nonacog | (see -cog) | |
-nonakin | (see -kin) | |
-octacog | (see -cog) | |
-octakin | (see -kin) | |
-olol | Beta-blockers (propranolol type) | timolol; atenolol |
-olone | Steroids (not prednisolone derivatives) | minaxolone |
-onide | Topical steroids (acetal derivatives) | amcinonide |
-opilone | Epothilone | filopilone |
-orex | Anorexiants | fludorex |
-orphan | Narcotic antagonists/agonists dextro-(morphinan derivatives) | methorphan; dextrorphan |
-osuran | Urotensin receptor antagonists | palosuran |
-otilate | Hepatoprotectants, di-isopropyl-1,3-dithiol- malonate derivatives | mivotilate |
-oxacin | Antibacterials (quinolone derivatives) | difloxacin; ciprofloxacin |
-oxan | Alpha-adrenoceptor antagonists (benzodioxane derivatives) | imiloxan |
-oxanide | Antiparasitics (salicylanilide derivatives) | bromoxanide |
-oxef | Antibiotics (oxacefalosporanic acid derivatives) | flomoxef |
-oxetine | Antidepressants (fluoxetine type) | dapoxetine; seproxetine |
-pafant | Platelet-activating factor antagonists | apafant; dacopafant; tulopafant; lexipafant |
-pamide | Diuretics (sulfamoylbenzoic acid derivatives) | alipamide |
-pamil | Coronary vasodilators (verapamil type) | tiapamil |
-pamine | Dopaminergics (butopamine type) | fosopamine; ibopamine |
-panel | AMPA receptor antagonists | fanapanel; irumpanel; talampanel |
-parcil | Antithrombotics | beciparcil; iliparcil |
-parcin | Glycopeptide antibiotics | avoparcin |
-parin | Heparin derivatives and low molecular weight (or depolymerized) heparins | heparin; tinzaparin; dalteparin |
-parinux | Antithrombotyic indirect selective synthetic factor Xa inhibitors | fondaparinux |
-paroid | Antithrombotics (heparinoid type) | danaparoid; sulparoid |
peg- | PEGylated compounds | pegcaristim; pegnartograstim;pegvisomant |
-penem | Antibacterial antibiotics (carbapenem derivatives) | imipenem |
-penkin | (see -kin) | |
perflu- | Blood substitutes and/or diagnostics (perfluorochemicals) | perflubron; perflunafene |
-peridol | Antipsychotics (haloperidol type) | haloperidol |
-peridone | Antipsychotics (risperidone type) | risperidone; iloperidone; ocaperidone |
-perone | Antianxiety agents/neuroleptics (4'-fluoro-4-piperidinobutyrophenone derivatives) | duoperone |
-pezil | Acetylcholinesterase inhibitors used in the treatment of Alzheimer’s disease | icopezil; donepezil |
-pidem | Hypnotics/sedatives (zolpidem type) | zolpidem; alpidem |
-pirdine | Cognition enhancers | linopirdine; besipirdine; sibopirdine |
-pirox | Antimycotics (pyridone derivatives) | ciclopirox |
-pitant | (see -tant) | |
-plact | Platelet factor 4 analogs and derivatives | iroplact |
-pladib | Phospholipase A2 inhibitors | ecopladib |
-planin | Antibacterials (Actinoplanes strains) | mideplanin; ramoplanin; teicoplanin |
-platin | Antineoplastics (platinum derivatives) | cisplatin |
-plasninin | Inhibitors of plasminogen activator inhibitors – type 1 | tiplasninin |
-plermin | (see -ermin) | |
-plestim | (see -stim) | |
-plon | Non-benzodiazepine anxiolytics, sedatives, hypnotics | ocinaplon; zaleplon |
-poetin | Erythropoietins | epoetin alfa; epoetin beta |
-porfin | Benzoporphyrin derivatives | verteporfin; temoporfin |
-pramine | Antidepressants (imipramine type) | lofepramine |
-prazan | Acid pump inhibitors, not dependent on acid activation | omidaprazan |
-prazole | Antiulcer agents (benzimidazole derivatives) | omeprazole; disuprazole |
subgroup: |
-maprazole | Antiulcer agents (benzimidazole derivatives); acid pump inhibitors | pumaprazole |
pred-, -pred- or -pred | Prednisone and prednisolone derivatives | prednicarbate; cloprednol; oxisopred |
-pressin | Vasoconstrictors (vasopressin derivatives) | desmopressin |
-pride | Sulpiride derivatives | remoxipride; zacopride |
-pril | Antihypertensives (ACE inhibitors) | enalapril; temocapril; spirapril |
-prilat | Antihypertensives (ACE inhibitors) (diacid analogs of the -pril entity) | enalaprilat; spiraprilat |
-prinim | Nootropic agents, purine derivatives | leteprinim |
-prim | Antibacterials (trimethoprim type) | ormetoprim |
-prisnil | Selective progesterone receptor modulators (SPRM) | asoprisnil |
-pristin | Antibacterials, pristinamycin derivatives | quinupristin; efepristin |
-pristone | Progesterone receptor antagonists | mifepristone |
-profen | Anti-inflammatory/analgesic agents (ibuprofen type) | flurbiprofen |
-prost- or -prost | Prostaglandin derivatives | rioprostil; dinoprost |
-protafib | Protein tyrosine phosphatase 1B inhibitors | ertiprotafib |
-pultide | (see -tide) | |
-proget | Nonsteroidal ligand for the progesterone receptor | tanaproget |
-queside | Cholesterol sequestrants (glycosides) | pamaqueside |
-racetam | Nootropes (piracetam type) | piracetam |
-racil | Uracil type antineoplastics | eniluracil; gemeracil; oteracil |
-relin | Prehormones or hormone-release stimulating peptides subgroups: | nafarelin |
subgroups: |
-morelin | Growth hormone-release stimulating peptides | dumorelin |
-tirelin | Thyrotropin releasing hormone analogues | protirelin |
-relix | Hormone-release inhibiting peptides aldosterone antagonists (spironolactone type) | detirelix |
-renone | Aldosterone antagonists (spironolactone type) | canrenone |
-restat | (see -stat) | |
-retin- or -retin | Retinol derivatives | etretinate; pelretin |
-rev | Therapeutic virus | |
subgroup: |
-tucirev | Therapeutic virus; tumoricidal | lontucirev |
-ribine | Ribofuranil derivatives (pyrazofurin type) | loxoribine |
rifa- | Antibiotics (rifamycin derivatives) | rifapentine; rifampin |
-rinone | Cardiotonics (amrinone type) | milrinone |
-rozole | Aromatase inhibitors (imidazole/triazole derivatives) | letrozole; fadrozole; vorozole |
-rsen | Antisense oligonucleotides | alicaforsen |
-rubicin | Antineoplastic antibiotics (daunorubicin type) | esorubicin; idarubicin |
sal-, -sal- or -sal | Anti-inflammatory agents (salicylic acid derivatives) | mesalamine; diflunisal; balsalazide |
-sartan | Angiotensin II receptor antagonists | losartan; eprosartan |
-semide | Diuretics (furosemide type) | azosemide |
-sermin | (see -ermin) | |
-serod | Serotonin receptor antagonists and partial agonists | piboserod |
-serpine | Rauwolfia alkaloid derivatives | reserpine |
-setron | Serotonin 5-HT3 antagonists | ondansetron; granisetron; lurosetron |
-siban | Oxytocin antagonists | barusiban |
-sidomine | Antianginals (sydnone derivatives) | pirsidomine; molsidomine; linsidomine |
som- | Growth hormone derivatives | somatrem; somatropin |
subgroups: |
som- -bove | Growth hormone derivatives; bovine somatotropin derivatives | sometribove |
som- -por | Growth hormone derivatives; porcine somatotropin derivatives | sometripor; somagrepor |
-sonan | 5-HT1B receptor antagonists | elzasonan |
-spirone | Anxiolytics (buspirone type) | zalospirone; tiospirone |
-spodar | (see -dar) | |
-sporin | Immunosuppressants (cyclosporine type) | geclesporin; oxeclosporin |
-stat-, -stat | Enzyme inhibitors | |
subgroups: |
-castat | Enzyme inhibitors; dopamine beta-hydrolase (DBH) inhibitors | nepicastat |
-elestat | Enzyme inhibitors; elastase inhibitors | sivelestat |
-inostat | Enzyme inhibitors; inhibitors of histone deacetylase | dacinostat |
-mastat | Enzyme inhibitors; antineoplastics (matrix metalloproteinase inhibitors) | batimastat |
-(a)mostat | Enzyme inhibitors; proteolytic enzyme inhibitors | nafamostat |
-restat- or -restat | Aldose-reductase inhibitors | ponalrestat; tolrestat |
-vastatin | Antihyperlipidemics (HMG-CoA inhibitors) | atorvastatin; lovastatin; pravastatin |
-urestat | Urease inhibitor | benurestat |
-stat- | Renal dehydropeptidase inhibitor | cilastatin |
-stat- | Pepsin inhibitor | pepstatin |
-statin | Renal dehydropeptidase inhibitor pepsin inhibitor | cilastatin; pepstatin |
-ster- | Steroids (androgens, anabolics) | testosterone |
-steride | Testosterone reductase inhibitors | epristeride; fenasteride |
-stigmine | Cholinesterase inhibitors (physostigmine type) | quilostigmine; teserstigmine |
-stim | Colony-stimulating factors | |
subgroups: |
-distim | Colony-stimulating factors; conjugates of two different types of colony-stimulating factors | milodistim |
-gramostim | Colony-stimulating factors; granulocyte macrophage colony- stimulating factors (GM-CSF) | molgramostim; regramostim; sargramostim; ecogramostim |
-grastim | Colony-stimulating factors; granulocyte colony-stimulating factors (G-CSF) | filgrastim; lenograstim |
-mostim | Colony-stimulating factors; macrophage colony-stimulating factors (M-CSF) | mirimostim |
-plestim | Colony-stimulating factors; interleukin 3 derivatives; pleiotropic colony-stimulating factors | daniplestim |
-stinel | NMDA receptor antagonists (glycine recognition site) | licostinel |
-sulam | Antineoplastics, apoptosis inducing sulfonamide | indisulam |
sulfa- | Antimicrobials (sulfonamides derivatives) | sulfasalazine |
-sulfan | Antineoplastics, alkylating agents (methanesulfonate derivatives) | busulfan |
-sulind | (see -lind) | |
-tant | Tachykinin (neurokinin) receptor antagonists | |
subgroups: |
-dutant | Tachykinin (neurokinin) receptor antagonists; NK2 receptor antagonists | saredutant |
-netant | Tachykinin (neurokinin) receptor antagonists; NK3 receptor antagonists | osanetant |
-pitant | Tachykinin (neurokinin) receptor antagonists; NK1 receptor antagonists | dapitant; zinapitant; lanepitant |
-tapide | Microsomal triglyceride transfer protein (MTP) inhibitors | implitapide |
-taxel | Antineoplastics, taxane derivatives | paclitaxel |
-tecan | Antineoplastics (camptothecine derivatives) | topotecan; irinotecan |
-tecarin | Antineoplastics (rebeccamycin derivatives) | becatecarin |
-tepa | Antineoplastics (thiotepa derivatives) | azetepa |
-teplase | (see -ase) | |
-termin | (see -ermin) | |
-terol | Bronchodilators (phenethylamine derivatives) | albuterol |
-tesind | Thymidilate synthetase inhibitors (benzindole derivatives) | metesind |
-texafin | Texaphryn derivatives | motexafin |
-thiazide | Diuretics (thiazide derivatives) | chlorothiazide |
-tiapine | Antipsychotics (dibenzothiazepine derivatives) | quitiapine |
-tiazem | Calcium channel blockers (diltiazem type) | diltiazem; clentiazem; iprotiazem |
-tibant | Antiasthmatics (bradykinin antagonists) | icatibant |
-tide | Peptides and glycopeptides | octreotide |
subgroups: |
-fibatide | Peptides and glycopeptides; platelet aggregation inhibitors (glycoprotein IIb/IIIa receptor antagonists) | eptifibatide |
-pultide | Peptides and glycopeptides; peptides used as pulmonary surfactants | sinapultide |
-tidine | H2-receptor antagonists (cimetidine type) | lupitidine; ranitidine; donetidine |
-tinib | Tyrosine kinase inhibitors | canertinib; imatinib; mubritinib |
-tirelin | (see -relin) | |
-tirome | Antihyperlidaemic, thyromimetic derivatives | anitirome; axitirome |
-tocin | Oxytocin derivatives | oxytocin |
-toclax | Antineoplastic, BLC-2 inhibitor | obatoclax |
-toin | Antiepileptics (hydantoin derivatives) | albutoin |
-toran | TLR4 receptor antagonists | eritoran |
-tox(a)- | Toxins | urtoxazumab |
-traposin | AP2 inhibitors | seltraposin |
-trexate | Antimetabolites (folic acid derivatives) | methotrexate |
-trexed | Antineoplastic thymidylate synthetase inhibitors | pemetrexed; ralitrexed; nolatrexed |
-tricin | Antibiotics (polyene derivatives) | mepartricin |
-tril -trilat | Endopeptidase inhibitors | candoxatril; candoxatrilat |
-triptan | Antimigraine agents (5-HT1 receptor agonists) | naratriptan; oxitriptan; sumatriptan |
-triptyline | Antidepressants (dibenzo[a,d]cycloheptane derivatives) | amitriptyline |
-troban | Antithrombotics (thromboxane A2 receptor antagonists) | daltroban; sulotroban |
-trodast | (see -ast) | |
-troline | Antipsychotics (dopamine D2 antagonists) | carvotroline; gevotroline |
-trombopag | Thrombopoetin agonists | eltrombopag |
trop- or -trop- | Atropine derivatives | benztropine |
-uclin | Mucosal tolerance inhibitors | |
-uplase | (see -ase) | |
-uracil | Uracil derivatives used as thyroid antagonists and as antineoplastics | fluorouracil |
-uridine | Antivirals; antineoplastics (uridine derivatives) | idoxuridine |
-vaptan | Vasopressin receptor antagonists | conivaptan; relcovaptan |
-vastatin | (see -stat) | |
-verine | Spasmolytic agents (papaverine type) | mebeverine |
vin- or -vin- | Vinca alkaloids | vinepidine; apovincamine |
vir-, -vir- or -vir | Antiviral substances (undefined group) | ganciclovir; enviradine; viroxime; alvircept; delavirdine |
subgroups: |
-amivir | Antiviral substances; neuraminidase inhibitors | zanamivir |
-cavir | Antiviral substances; carbocyclic nucleosides | lobucavir |
-cyclovir | Antiviral substances; (acyclovir type) | acyclovir |
-ciclovir | Antiviral substances; (acyclovir type) | desciclovir; famciclovir; penciclovir |
-gosivir | Antiviral substances; glucosidase inhibitor | celgosivir |
-navir | Antiviral substances; HIV protease inhibitors (saquinavir type) | droxinavir; indinavir; ritonavir |
-virdine | Antiviral substances; (non-nucleoside reverse transcriptase inhibitors; pyridine derivatives) | atevirdine; delevirdine |
-virenz | Antivirals (non-nucleoside reverse transcriptase inhibitors; benzoxazinone derivatives) | efavirenz |
-virsen | Antivirals (antisense) | afovirsen; fomivirsen; trecovirsen |
-vircept | (see -cept) | |
-virdine | (see -vir) | |
-virenz | (see -vir) | |
-virimat | Antiviral, disrupts viral maturation | bevirimat |
-viroc | CCR5 antagonists | maraviroc |
subgroup: |
-criviroc | CCR5 antagonists, immunomodulators | ancriviroc |
-vudine | Antineoplastics; antivirals (zidovudine group) (exception: edoxudine) | stavudine; lamivudine; alovudine |
-xaban | Anticoagulant (Factor Xa inhibitor) | tamixaban |
-xanox | Antiallergic respiratory tract drugs (xanoxic acid derivatives) | tixanox |
-(x)antrone | Antineoplastics, mitoxantrone derivatives aza-anthracenedione class of antitumor agents | pixantrone |
-zolamide | Carbonic anhydrase inhibitors | brinzolamide; dorzolamide; sezolamide |
-zolast | (see -ast) | |
-zomib | Proteozome inhibitors | bortezomib |
-zotan | 5-HT1A receptor agonists/antagonists acting primarily as neuroprotectors | robalzotan; sarizotan; ibalzotan; lecozotan |
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